Author

R. Parton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Organism:zebrafish· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

J. Rae· 2 shared T. Hall· 2 shared A. K. Lagendijk· 1 shared A. Lagendijk· 1 shared A. Pettit· 1 shared A. Yap· 1 shared B. Collins· 1 shared B. Gliddon· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

J. Rae

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic metabolism to fuel growth.

S. Kesvari, J. Masson, M. Ferrari-Cestari, L.-G. Bodea, F. Nooru-Mohamed, B. Tse, K. Sokolowski, L. Batoon, O. Patkar, M. Sullivan, H. Ebersbach, C. Stutz, R. Parton, A. Pettit, D. Hume, K. M. Irvine

This study shows that CSF1 increases tissue macrophages and alters systemic metabolism, including glucose uptake and fat mobilization, with reversible effects on liver size and body composition.

bioRxiv · May 17, 2023 · PreprintImmunology

Macrophages only sense infectious SARS-CoV-2 when they express sufficient ACE2 to permit viral entry, where rapid cytokine responses then limit viral replication.

L. I. Labzin, K. Y. Chew, K. Eschke, X. Wang, T. Esposito, C. J. Stocks, J. Rae, R. Patrick, H. Mostafavi, B. Hill, T. Yordanov, C. L. Holley, S. Emming, S. Fritzlar, F. L. Mordant, , K. Schroder

The paper shows that ACE2-expressing macrophages allow SARS-CoV-2 entry and replication, triggering anti-viral responses, while ACE2-negative macrophages do not support viral entry or cytokine release.

bioRxiv · Mar 22, 2022 · PreprintImmunology

Muscle-specific Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle

H. Lo, Y.-W. Lim, Z. Xiong, N. Martel, C. Ferguson, N. Ariotti, J. Giacomotto, J. Rae, M. Floetenmeyer, S. V. Moradi, Y. Gao, V. Tillu, D. Xia, H. Wang, S. Rahnama, , R. Parton

This study identifies Cavin4's role in T-tubule formation and stability in skeletal muscle by showing its interaction with Bin1 and effects on caveolae remodeling.

bioRxiv · Jan 13, 2021Cell Biology

A unified view of neighbour cell engagement during apoptotic cell extrusion.

K. Duszyc, G. Gomez, A. Lagendijk, M.-K. Yau, B. Gliddon, T. Hall, S. Verma, B. Hogan, S. Pitson, D. Fairlie, R. Parton, A. Yap

This study identifies RhoA activation via a Myosin VI-dependent mechanotransduction pathway as the mechanism by which apoptotic cells engage neighboring cells for extrusion, with S1P providing priming.

bioRxiv · Aug 6, 2020 · PreprintCell Biology