Author

H. Goossens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:whole-genome sequencing· 4 Approach:experimental assay· 3 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:clinical cohort / trial· 1 Research Focus:clustering· 1

Frequent Co-Authors

C. Lammens· 3 shared J. Rodriguez-Bano· 2 shared S. Malhotra-Kumar· 2 shared T. Kostyanev· 2 shared A. Arenzana· 1 shared A. Oliver· 1 shared A. Quinn· 1 shared A. Ruzin· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersMicrobiology

C. Lammens

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

International and regional spread of carbapenem-resistant Klebsiella pneumoniae in Europe

M. Budia Silva, T. Kostyanev, S. Ayala Montano, J. M. Bravo-Ferrer Acosta, M. Garcia-Castillo, R. Canton, H. Goossens, J. Rodriguez-Bano, H. Grundmann, S. Reuter, EURECA/WP1B Group

This study analyzes genomic data of carbapenem-resistant K. pneumoniae strains from Europe to identify clonal complexes and carbapenemase genes, revealing regional differences in their spread.

bioRxiv · Sep 5, 2023 · PreprintMicrobiology

Harmonization of whole genome sequencing for outbreak surveillance of Enterobacteriaceae and Enterococci

C. Jamin, S. de Koster, S. van Koeveringe, D. de Coninck, K. Mensaert, K. de Bruyne, N. Perales Selva, C. Lammens, H. Goossens, C. J. Hoebe, P. Savelkoul, L. B. van Alphen

This study demonstrates that harmonized whole genome sequencing across multiple centers is achievable for bacterial outbreak surveillance, achieving high precision and accuracy in genotyping and MLST analysis.

bioRxiv · Nov 20, 2020Microbiology

Rapid evolution drives the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection

R. Wheatley, J. Diaz Caballero, N. Kapel, A. Quinn, E. del Barrio-Tofino, C. Lopez-Causape, J. Hedge, G. Torrens, T. Van der Schalk, B. Britto Xavier, F. Fernandez-Cuenca, A. Arenzana, C. Recanatini, L. Timbermont, F. Sifakis, , C. MacLean

The paper tracks the rapid evolution of carbapenem resistance in P. aeruginosa during an acute infection, showing resistance rise and fall due to antibiotic treatment.

bioRxiv · Aug 10, 2020Evolutionary Biology

Evaluation of a Loop-Mediated Isothermal Amplification assay to detect carbapenemases from Acinetobacter spp. directly from bronchoalveolar lavage fluid

J. Moreno-Morales, A. Vergara, T. Kostyanev, J. Rodriguez-Bano, H. Goossens, J. Vila

The paper evaluates a LAMP assay for rapid detection of carbapenemases in Acinetobacter spp. from bronchoalveolar lavage fluid with high sensitivity.

bioRxiv · May 11, 2020Microbiology

Comparison of biofilm dispersal approaches in Pseudomonas aeruginosa and evaluation of dispersed cells in acute infection mouse model

R. Ruhal, F. De Winter, B. de Jonger, B. B. Xavier, C. Lammens, H. Goossens, S. Kumar Singh, S. Malhotra-Kumar

This study compares biofilm dispersal methods in Pseudomonas aeruginosa and evaluates their ability to cause acute infections in mice, finding that efficient dispersal methods increase mortality.

bioRxiv · Jul 10, 2019 · PreprintMicrobiology

Comparative genomic analysis of the emerging pathogen Streptococcus pseudopneumoniae: novel insights into virulence determinants and identification of a novel species-specific molecular marker

G. Garriss, P. Nannapaneni, A. S. Simoes, S. Brovall, R. Sa-Leao, H. Goossens, H. de Lencastre, B. Henriques-Normark

This study identifies a novel molecular marker for Streptococcus pseudopneumoniae and analyzes its virulence, colonization, and antimicrobial resistance genes.

bioRxiv · Nov 12, 2018 · PreprintMicrobiology