Author

B. Schouest

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Microbiology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 7 Organism:non-human primate· 5 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

N. J. Maness· 4 shared A. Panganiban· 3 shared A. Doan· 2 shared A. Singapuri· 2 shared A. T. Panganiban· 2 shared D. B. Weiner· 2 shared D. Elwood· 2 shared F. Schiro· 2 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersImmunology

N. J. Maness

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Zika virus persistence in the male macaque reproductive tract

E. E. Ball, P. A. Pesavento, K. K. A. Van Rompay, M. K. Keel, A. Singapuri, J. P. Gomez-Vazquez, D. M. Dudley, D. OConnor, M. E. Breitbach, N. Maness, B. Schouest, A. Panganiban, L. L. Coffey

This study investigates ZIKV persistence in male macaque reproductive tissues, finding prolonged viral presence in germ and epithelial cells and potential impacts on fertility.

bioRxiv · Mar 3, 2022Pathology

Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates

J. N. Walters, B. Schouest, A. Patel, E. L. Reuschel, K. Schultheis, E. Parzych, I. Maricic, E. N. Gary, M. Purwar, V. M. Andrade, A. Doan, D. Elwood, Z. Eblimit, B. Nguyen, D. Frase, , K. E. Broderick

bioRxiv · Oct 27, 2021Immunology

Design, immunogenicity and efficacy of a Pan-SARS-CoV-2 synthetic DNA vaccine

C. C. Reed, K. Schultheis, V. M. Andrade, R. Kalia, J. Tur, B. Schouest, D. Elwood, J. N. Walters, I. Maricic, A. Doan, M. Vazquez, Z. Eblimit, P. Pezzoli, D. Amante, M. Porto, , K. E. Broderick

This study designs and tests a DNA vaccine, INO-4802, which induces broad immunity against multiple SARS-CoV-2 variants in animal models.

bioRxiv · May 11, 2021 · PreprintImmunology

Zika virus infection during pregnancy protects against secondary infection in the absence of CD8+ cells

B. Schouest, M. H. Gilbert, R. P. Bohm, F. Schiro, P. P. Aye, A. T. Panganiban, D. M. Magnani, N. J. Maness

This study shows that ZIKV infection during pregnancy provides protection against secondary infection without relying on CD8+ cells.

bioRxiv · May 8, 2020Immunology

A Zika Virus Primary Isolate Induces Neuroinflammation, Compromises the Blood-Brain Barrier, and Upregulates CXCL12 in Adult Macaques

A. Panganiban, R. V. Blair, J. B. Hattler, D. G. Bohannon, M. C. Bonaldo, B. Schouest, N. J. Maness, W.-K. Kim

This study investigates ZIKV-induced neuropathy in adult macaques, finding chronic neuroinflammation, BBB disruption, and sustained CXCL12 upregulation in the CNS.

bioRxiv · Nov 20, 2019Microbiology

Brief report: Mutations in SIV Nef that disrupt and restore tetherin downregulation

N. J. Maness, B. Schouest

The paper identifies a mutation in SIV Nef that disrupts tetherin downregulation and shows that an upstream residue can restore this function.

bioRxiv · Nov 6, 2019Immunology

CD8+ lymphocytes modulate Zika virus dynamics and tissue dissemination and orchestrate antiviral immunity

B. Schouest, M. Fahlberg, E. A. Scheef, M. J. Ward, K. Headrick, D. M. Szeltner, R. V. Blair, M. H. Gilbert, L. A. Doyle-Meyers, V. W. Danner, M. C. Bonaldo, D. M. Wesson, A. T. Panganiban, N. J. Maness

This study shows CD8+ lymphocytes control ZIKV dissemination and immune regulation in nonhuman primates by affecting viremia, tissue viral loads, and immune responses.

bioRxiv · Jul 11, 2019 · PreprintImmunology

Maternal antibodies provide partial protection from postnatal Zika viremia in nonhuman primates

N. Maness, B. Schouest, A. Singapuri, M. Dennis, M. Gilbert, R. Bohm, F. Schiro, P. Aye, K. Baker, K. Van Rompay, A. Lackner, M. Bonaldo, R. Blair, S. Permar, L. Coffey, , D. Magnani

This study shows that maternal antibodies provide partial protection against postnatal Zika virus infection in infant nonhuman primates, reducing viremia but not completely preventing viral dissemination.

bioRxiv · Apr 18, 2019Microbiology