Author

R. Kalia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

A. Frost· 3 shared D. B. Weiner· 2 shared D. Elwood· 2 shared J. J. Kim· 2 shared J. Tur· 2 shared K. E. Broderick· 2 shared K. Schultheis· 2 shared L. M. Humeau· 2 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCell Biology

A. Frost

Author profile →

5 papers

Recent·Most cited

Design, immunogenicity and efficacy of a Pan-SARS-CoV-2 synthetic DNA vaccine

C. C. Reed, K. Schultheis, V. M. Andrade, R. Kalia, J. Tur, B. Schouest, D. Elwood, J. N. Walters, I. Maricic, A. Doan, M. Vazquez, Z. Eblimit, P. Pezzoli, D. Amante, M. Porto, , K. E. Broderick

This study designs and tests a DNA vaccine, INO-4802, which induces broad immunity against multiple SARS-CoV-2 variants in animal models.

bioRxiv · May 11, 2021 · PreprintImmunology

INO-4800 DNA Vaccine Induces Neutralizing Antibodies and T cell Activity Against Global SARS-CoV-2 Variants

V. M. Andrade, A. Christensen-Quick, J. Agnes, J. Tur, C. Reed, R. Kalia, I. Marrero, D. Elwood, K. Schultheis, M. Purwar, E. Reuschel, T. McMullan, P. Pezzoli, K. Kraynyak, A. Sylvester, , K. E. Broderick

This study evaluates the efficacy of the INO-4800 DNA vaccine against SARS-CoV-2 variants, showing neutralizing antibodies and preserved T cell responses.

bioRxiv · Apr 14, 2021Immunology

The mechanisms of dynamin-actin interaction

R. Zhang, N. Gerassimov, D. M. Lee, J. R. Jimah, S. Kim, D. Luvsanjav, J. Winkelman, M. Mettlen, M. E. Abrams, R. Kalia, P. Keene, P. Pandey, B. Ravaux, J. H. Kim, J. A. Ditlev, , E. H. Chen

This study identifies a noncanonical role for dynamin in cell-cell fusion by directly bundling actin filaments through GTPase-dependent interactions.

bioRxiv · Mar 25, 2019 · PreprintCell Biology

Vms1p is a release factor for the Ribosome-associated Quality control Complex

O. Z. Rendon, E. K. Fredrickson, C. J. Howard, J. V. Vranken, S. Fogarty, N. D. Tolley, R. Kalia, B. A. Osuna, P. S. Shen, C. P. Hill, A. Frost, J. Rutter

This study identifies Vms1p as the tRNA hydrolase that releases nascent polypeptides in the RQC pathway for degradation.

bioRxiv · Apr 14, 2018Biochemistry

Structural Basis of Mitochondrial Receptor Binding and GTP Driven Conformational Constriction by Dynamin-Related Protein 1

R. Kalia, R. Y.- R. Wang, A. Yusuf, P. V. Thomas, D. A. Agard, J. M. Shaw, A. Frost

This study presents cryoEM structures of DRP1 bound to MID49 and nucleotides, revealing how GTP binding drives conformational changes essential for mitochondrial fission.

bioRxiv · Aug 7, 2017Biophysics