Author

H. J. Stauss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. R. Teagle· 1 shared C. Christodoulidou· 1 shared C. Georgiou· 1 shared C. L. Lo Celso· 1 shared C. Pospori· 1 shared D. Bonnet· 1 shared D. Stampoulis· 1 shared D. Wright· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. R. Teagle

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Dynamic regulation of hierarchical heterogeneity in Acute Myeloid Leukemia serves as a tumor immunoevasion mechanism

C. Pospori, W. Grey, S. Gonzalez-Anton, S. V. Gibson, C. Georgiou, F. Birch, G. Stevens, T. Williams, R. Khorshed, M. L. R. Haltalli, M.-N. Skoufou-Papoutsaki, K. Sloan, H. H. Encabo, J. Hopkins, C. Christodoulidou, , C. L. Lo Celso

The paper shows that hierarchical heterogeneity in AML cells, regulated by immune responses, contributes to disease progression through PDL1 upregulation and dynamic balance between proliferation and immunosuppression.

bioRxiv · Dec 21, 2020 · PreprintCancer Biology

CRISPR-mediated deletion of the Protein tyrosine phosphatase, non-receptor type 22 (PTPN22) improves human T cell function for adoptive T cell therapy

S. Prade, D. Wright, N. Logan, A. R. Teagle, H. J. Stauss, R. Zamoyska

This study shows that deleting PTPN22 in human T cells enhances their cytokine production and anti-tumor activity, suggesting improved function in the tumor microenvironment.

bioRxiv · Dec 3, 2020 · PreprintImmunology