Author

H. K. Li

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Vieira· 4 shared S. Sriskandan· 4 shared X. Zhi· 4 shared E. Jauneikaite· 3 shared J. Coelho· 3 shared K. K. Huse· 3 shared H. Li· 2 shared I. Andrew· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

A. Vieira

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Characterization of the RofA regulon in the pandemic M1global and emergent M1UK lineages of Streptococcus pyogenes

X. Zhi, A. Vieira, K. K. Huse, P. J. Martel, L. Lobkowicz, H. K. Li, N. Croucher, I. Andrew, L. Game, S. Sriskandan

This study characterizes the RofA regulon in two emm1 lineages of Streptococcus pyogenes, showing lineage-specific gene expression changes and potential regulatory impacts of SNPs in the PRD domain.

bioRxiv · Jul 23, 2023 · PreprintMicrobiology

Multi-continental detection of Streptococcus pyogenes M1UK: Impact of ssrA SNP on SpeA expression in ancestral and M1UK isolates

A. Vieira, H. K. Li, X. Zhi, L. Reeves, K. K. Huse, K. Y. Mok, O. Cowen, E. Jauneikaite, J. Coelho, S. Sriskandan, V. W. Soo

This study investigates the impact of an ssrA SNP on SpeA expression in Streptococcus pyogenes isolates, showing its role in enhancing SpeA production but not being the sole determinant.

bioRxiv · Apr 30, 2023 · PreprintMicrobiology

Characterisation of emergent toxigenic M1UK Streptococcus pyogenes and associated sublineages

H. K. Li, X. Zhi, A. Vieira, H. J. Whitwell, A. Schricker, E. Jauneikaite, H. Li, A. Yosef, I. Andrew, L. Game, C. E. Turner, T. Lamagni, J. Coelho, S. Sriskandan

This study characterizes the M1UK sublineage of Streptococcus pyogenes, identifying genetic and phenotypic differences that contribute to its dominance and increased virulence.

bioRxiv · Dec 27, 2022Microbiology

Ongoing emergence of M1UK lineage among invasive group A streptococcus isolates in 2020 and use of allele-specific PCR

X. Zhi, H. K. Li, H. Li, Z. Loboda, S. Charles, A. Vieira, K. K. Huse, E. Jauneikaite, J. Coelho, T. Lamagni, S. Sriskandan

The paper develops an allele-specific PCR to subtype emm1 Streptococcus pyogenes isolates, finding M1UK lineage dominates invasive infections in England in 2020.

bioRxiv · Dec 18, 2022Microbiology