Author

A. Vieira

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:genetic perturbation / CRISPR· 2

Frequent Co-Authors

S. Sriskandan· 5 shared X. Zhi· 5 shared E. Jauneikaite· 4 shared H. K. Li· 4 shared J. Coelho· 3 shared K. K. Huse· 3 shared H. Li· 2 shared I. Andrew· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

S. Sriskandan

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Characterization of the RofA regulon in the pandemic M1global and emergent M1UK lineages of Streptococcus pyogenes

X. Zhi, A. Vieira, K. K. Huse, P. J. Martel, L. Lobkowicz, H. K. Li, N. Croucher, I. Andrew, L. Game, S. Sriskandan

This study characterizes the RofA regulon in two emm1 lineages of Streptococcus pyogenes, showing lineage-specific gene expression changes and potential regulatory impacts of SNPs in the PRD domain.

bioRxiv · Jul 23, 2023 · PreprintMicrobiology

Multi-continental detection of Streptococcus pyogenes M1UK: Impact of ssrA SNP on SpeA expression in ancestral and M1UK isolates

A. Vieira, H. K. Li, X. Zhi, L. Reeves, K. K. Huse, K. Y. Mok, O. Cowen, E. Jauneikaite, J. Coelho, S. Sriskandan, V. W. Soo

This study investigates the impact of an ssrA SNP on SpeA expression in Streptococcus pyogenes isolates, showing its role in enhancing SpeA production but not being the sole determinant.

bioRxiv · Apr 30, 2023 · PreprintMicrobiology

Characterisation of emergent toxigenic M1UK Streptococcus pyogenes and associated sublineages

H. K. Li, X. Zhi, A. Vieira, H. J. Whitwell, A. Schricker, E. Jauneikaite, H. Li, A. Yosef, I. Andrew, L. Game, C. E. Turner, T. Lamagni, J. Coelho, S. Sriskandan

This study characterizes the M1UK sublineage of Streptococcus pyogenes, identifying genetic and phenotypic differences that contribute to its dominance and increased virulence.

bioRxiv · Dec 27, 2022Microbiology

Ongoing emergence of M1UK lineage among invasive group A streptococcus isolates in 2020 and use of allele-specific PCR

X. Zhi, H. K. Li, H. Li, Z. Loboda, S. Charles, A. Vieira, K. K. Huse, E. Jauneikaite, J. Coelho, T. Lamagni, S. Sriskandan

The paper develops an allele-specific PCR to subtype emm1 Streptococcus pyogenes isolates, finding M1UK lineage dominates invasive infections in England in 2020.

bioRxiv · Dec 18, 2022Microbiology

Diverse Genetic Determinants of Nitrofurantoin Resistance in UK Escherichia coli

Y. Wan, E. Mills, R. C. Y. Leung, A. Vieira, E. Jauneikaite, X. Zhi, N. J. Croucher, N. Woodford, M. J. Ellington, S. Sriskandan

This study identifies genetic factors causing nitrofurantoin resistance in UK E. coli, finding mutations and insertion sequences in nfsA and nfsB as major contributors.

bioRxiv · May 27, 2021Microbiology

Light-entrained and brain-tuned circadian circuits regulate ILC3 and gut homeostasis

C. Godinho-Silva, R. G. Domingues, M. Rendas, B. Raposo, H. Ribeiro, J. Alves da Silva, A. Vieira, R. M. Costa, N. L. Barbosa-Morais, T. Carvalho, H. Veiga-Fernandes

This study shows that circadian circuits regulated by light and the brain control ILC3 function, gut homeostasis, and metabolism.

bioRxiv · Aug 27, 2019Immunology