Author

H. M. Bernstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:protein folding & dynamics· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. Imperiali· 4 shared A. Majumder· 1 shared B. A. Kashemirov· 1 shared C. A. Arbour· 1 shared C. M. McKenna· 1 shared G. J. Dodge· 1 shared H. C. Dorfmueller· 1 shared J. E. Straub· 1 shared

Activity by Year

2023-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersBiochemistry

B. Imperiali

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies

L. M. Seebald, P. Haratipour, M. R. Jacobs, H. M. Bernstein, B. A. Kashemirov, C. M. McKenna, B. Imperiali

This paper designs and synthesizes uridine bisphosphonates (UBPs) as chemical probes to study phosphoglycosyl transferase (PGT) superfamilies, finding structural and mechanistic differences in their ligand binding.

bioRxiv · Sep 19, 2023Biochemistry

Synergistic computational and experimental studies of a phosphoglycosyltransferase membrane/ligand ensemble

A. Majumder, N. Vuksanovic, L. C. Ray, H. M. Bernstein, K. N. Allen, B. Imperiali, J. E. Straub

This study combines computational and experimental approaches to investigate the interaction of undecaprenol phosphate with the phosphoglycosyltransferase PglC from Campylobacter, revealing insights into substrate recognition and binding mechanisms.

bioRxiv · May 7, 2023Biochemistry

A generalizable protocol for expression and purification of membrane-bound bacterial phosphoglycosyl transferases in liponanoparticles.

G. J. Dodge, H. M. Bernstein, B. Imperiali

This paper develops a protocol for expressing and purifying membrane-bound bacterial phosphoglycosyl transferases using liponanoparticles, achieving high purity and compatibility with CryoEM.

bioRxiv · Mar 20, 2023Biochemistry

Defining Early Steps in B. subtilis Biofilm Biosynthesis

C. A. Arbour, R. Nagar, H. M. Bernstein, S. Ghosh, Y. Al-Sammarraie, H. C. Dorfmueller, M. A. J. Ferguson, N. Stanley-Wall, B. Imperiali

This paper identifies the first two steps in the exopolysaccharide biosynthesis pathway of B. subtilis, determining the substrates for the key enzymes involved.

bioRxiv · Feb 22, 2023 · PreprintMicrobiology