Author

B. A. Kashemirov

Primary ORCID profile (0000-0001-7175-9960 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

B. A. KashemiroviD1 paper · University of Southern California

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

C. E. McKenna· 2 shared B. Imperiali· 1 shared C. Garnaud· 1 shared C. M. McKenna· 1 shared C. Petosa· 1 shared D. Liu· 1 shared G. Bourgine· 1 shared G. Rabut· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

C. E. McKenna

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies

L. M. Seebald, P. Haratipour, M. R. Jacobs, H. M. Bernstein, B. A. Kashemirov, C. M. McKenna, B. Imperiali

This paper designs and synthesizes uridine bisphosphonates (UBPs) as chemical probes to study phosphoglycosyl transferase (PGT) superfamilies, finding structural and mechanistic differences in their ligand binding.

bioRxiv · Sep 19, 2023Biochemistry

Targeting fungal BET bromodomains as a pan-Candida antifungal strategy

K. Wei, J. M. Overhulse, M. Arlotto, Y. Zhou, N. J. Dupper, B. A. Kashemirov, C. Garnaud, G. Bourgine, M. Cornet, G. Rabut, C. E. McKenna, C. Petosa, J. Govin

This study identifies a phenyltriazine compound that selectively targets both Bdf1 bromodomains in Candida species, showing antifungal activity against multiple Candida strains including resistant isolates.

bioRxiv · Feb 3, 2023 · PreprintBiochemistry

An Acyclic Phosphonate Prodrug of HPMPC is Effective Against VZV in Skin Organ Culture and Mice

M. G. Lloyd, D. Liu, J. Lyu, J. Fan, J. Overhulse, B. A. Kashemirov, M. N. Prichard, C. E. McKenna, J. F. Moffat

This study develops and evaluates USC-373, a phosphonate prodrug of HPMPC, showing efficacy against VZV in cell cultures and mouse models with improved potency and bioavailability.

bioRxiv · Jan 30, 2022Microbiology