Author

B. Imperiali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:bacteria (other)· 3 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 2 Assay:structural biology· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

H. M. Bernstein· 4 shared G. J. Dodge· 2 shared A. J. Anderson· 1 shared A. Majumder· 1 shared B. A. Kashemirov· 1 shared C. A. Arbour· 1 shared C. M. McKenna· 1 shared C. Y. Zamora· 1 shared

Activity by Year

2019-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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4 shared papersBiochemistry

H. M. Bernstein

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Uridine Bisphosphonates Differentiate Phosphoglycosyl Transferase Superfamilies

L. M. Seebald, P. Haratipour, M. R. Jacobs, H. M. Bernstein, B. A. Kashemirov, C. M. McKenna, B. Imperiali

This paper designs and synthesizes uridine bisphosphonates (UBPs) as chemical probes to study phosphoglycosyl transferase (PGT) superfamilies, finding structural and mechanistic differences in their ligand binding.

bioRxiv · Sep 19, 2023Biochemistry

Mapping the architecture of the initiating phosphoglycosyl transferase from S. enterica O-antigen biosynthesis in a liponanoparticle.

G. J. Dodge, A. J. Anderson, Y. He, W. Liu, R. Viner, B. Imperiali

This study stabilizes, purifies, and structurally characterizes a membrane-bound phosphoglycosyl transferase from Salmonella without detergent, revealing its dimeric structure and conserved motifs.

bioRxiv · Jun 16, 2023 · PreprintBiochemistry

Synergistic computational and experimental studies of a phosphoglycosyltransferase membrane/ligand ensemble

A. Majumder, N. Vuksanovic, L. C. Ray, H. M. Bernstein, K. N. Allen, B. Imperiali, J. E. Straub

This study combines computational and experimental approaches to investigate the interaction of undecaprenol phosphate with the phosphoglycosyltransferase PglC from Campylobacter, revealing insights into substrate recognition and binding mechanisms.

bioRxiv · May 7, 2023Biochemistry

A generalizable protocol for expression and purification of membrane-bound bacterial phosphoglycosyl transferases in liponanoparticles.

G. J. Dodge, H. M. Bernstein, B. Imperiali

This paper develops a protocol for expressing and purifying membrane-bound bacterial phosphoglycosyl transferases using liponanoparticles, achieving high purity and compatibility with CryoEM.

bioRxiv · Mar 20, 2023Biochemistry

Defining Early Steps in B. subtilis Biofilm Biosynthesis

C. A. Arbour, R. Nagar, H. M. Bernstein, S. Ghosh, Y. Al-Sammarraie, H. C. Dorfmueller, M. A. J. Ferguson, N. Stanley-Wall, B. Imperiali

This paper identifies the first two steps in the exopolysaccharide biosynthesis pathway of B. subtilis, determining the substrates for the key enzymes involved.

bioRxiv · Feb 22, 2023 · PreprintMicrobiology

Application of a gut-immune co-culture system for the study of N-glycan-dependent host-pathogen interactions of Campylobacter jejuni

C. Y. Zamora, E. M. Ward, J. C. Kester, W. L. K. Chen, J. G. Velazquez, L. G. Griffith, B. Imperiali

The paper uses a gut-immune co-culture model to study how N-glycan-dependent glycosylation affects Campylobacter jejuni's ability to adhere, invade, and modulate immune responses in intestinal cells.

bioRxiv · Jul 13, 2019Microbiology