Author

H. M. Ruetten

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. M. Vezina· 4 shared D. E. Bjorling· 2 shared H. L. Zhang· 2 shared K. A. Wegner· 2 shared M. Cadena· 2 shared P. Wang· 2 shared S. K. Sandhu· 2 shared W. A. Ricke· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersPhysiology

C. M. Vezina

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Author profile →

4 papers

Recent·Most cited

OSTEOPONTIN DEFICIENCY LEADS TO THE RESOLUTION OF PROSTATIC FIBROSIS AND INFLAMMATION

P. Popovics, A. Jain, K. O. Skalitzky, E. Schroeder, H. M. Ruetten, M. Cadena, K. S. Uchtmann, C. M. Vezina, W. A. Ricke

This study shows that OPN deficiency reduces inflammation and fibrosis in the prostate after E. coli infection in mice.

bioRxiv · Jul 19, 2021 · PreprintPathology

A Uropathogenic E. coli UTI89 model of prostatic inflammation and collagen accumulation for use in studying aberrant collagen production in the prostate

H. M. RUETTEN, J. Sandhu, B. Mueller, P. Wang, H. L. Zhang, K. A. Wegner, M. Cadena, S. Sandhu, L. Abler, J. Zhu, C. A. O'Driscoll, B. Chelgren, Z. Wang, T. Shen, J. Barasch, , C. M. Vezina

This paper develops a mouse model of prostatic inflammation and collagen accumulation using E. coli UTI89 instillations to study aberrant collagen production in the prostate.

bioRxiv · Aug 10, 2020Physiology

Urethral luminal epithelia are castration-insensitive progenitors of the proximal prostate

D. B. Joseph, G. H. Henry, A. Malewska, N. Iqbal, H. M. Ruetten, A. E. Turco, L. L. Abler, S. K. Sandhu, M. T. Cadena, V. S. Malladi, J. C. Reese, R. J. Mauck, J. C. Gahan, R. C. Hutchinson, C. G. Roehrborn, , D. W. Strand

The paper identifies urethral luminal epithelia as castration-insensitive progenitors of the proximal prostate using scRNA-seq and flow cytometry in mice and humans.

bioRxiv · Feb 19, 2020Cell Biology

Factors Driving Unique Urination Phenotypes of Male and Female 9-week-old C57BL/6J Mice

H. M. RUETTEN, K. A. Wegner, H. L. Zhang, P. Wang, J. K. Sandhu, S. K. Sandhu, B. R. Mueller, Z. Wang, J. Macoska, R. E. Peterson, D. E. Bjorling, W. A. Ricke, P. C. Marker, C. M. Vezina

This study evaluates how prostate mass and testosterone affect voiding function in male and female mice, finding that testosterone, not prostate size, primarily drives sex differences in urinary function.

bioRxiv · May 27, 2019Physiology