Author

P. Popovics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:differential expression· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Assay:protein sequence· 1

Frequent Co-Authors

C. M. Vezina· 3 shared W. A. Ricke· 3 shared A. Jain· 2 shared E. Schroeder· 2 shared K. O. Skalitzky· 2 shared K. S. Uchtmann· 2 shared M. M. Grabowska· 2 shared S. V. Silver· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersPathology

C. M. Vezina

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5 papers

Recent·Most cited

PROSTATE CELL HETEROGENEITY AND CXCL17 UPREGULATION IN MOUSE STEROID HORMONE IMBALANCE

S. V. Silver, K. J. Tucker, R. E. Vickman, N. A. Lanman, O. J. Semmes, N. S. Alvarez, P. Popovics

This study identifies CXCL17 upregulation and macrophage subsets in mouse prostate under steroid hormone imbalance, linking them to foam cell formation and inflammation.

bioRxiv · Apr 24, 2024 · PreprintPathology

Steroid hormone imbalance drives macrophage infiltration and Spp1/osteopontin+ foam cell differentiation in the prostate

P. Popovics, K. O. Skalitzky, E. Schroeder, A. Jain, S. V. Silver, F. Van Fritz, K. S. Uchtmann, C. M. Vezina, W. A. Ricke

This study shows that steroid hormone imbalance in mice increases macrophage infiltration and Spp1/osteopontin+ foam cell differentiation in the prostate, with OPN knockout reducing these effects.

bioRxiv · Dec 13, 2022Pathology

OSTEOPONTIN DEFICIENCY LEADS TO THE RESOLUTION OF PROSTATIC FIBROSIS AND INFLAMMATION

P. Popovics, A. Jain, K. O. Skalitzky, E. Schroeder, H. M. Ruetten, M. Cadena, K. S. Uchtmann, C. M. Vezina, W. A. Ricke

This study shows that OPN deficiency reduces inflammation and fibrosis in the prostate after E. coli infection in mice.

bioRxiv · Jul 19, 2021 · PreprintPathology

Increased nuclear factor I/B expression in prostate cancer correlates with AR expression

J. S. Nanda, W. N. Awadallah, S. E. Kohrt, P. Popovics, J. M. M. Cates, J. Mirosevich, P. E. Clark, G. A. Giannico, M. M. Grabowska

The paper examines NFIB expression in prostate cancer, showing its correlation with AR and its nuclear/cytoplasmic localization, and demonstrates an AR-NFIB interaction.

bioRxiv · Apr 14, 2020Cancer Biology

Prostatic osteopontin expression is associated with symptomatic benign prostatic hyperplasia

P. Popovics, W. N. Awadallah, S. Kohrt, T. C. Case, N. L. Miller, E. Ricke, W. Huang, M. Ramirez-Solano, Q. Liu, C. M. Vezina, R. J. Matusik, W. A. Ricke, M. M. Grabowska

This study shows that osteopontin (OPN) is more abundant in symptomatic benign prostatic hyperplasia (S-BPH) compared to incidental BPH, and OPN secretion is stimulated by pro-inflammatory cytokines, driving pro-inflammatory gene expression in stromal cells.

bioRxiv · Dec 23, 2019Pathology