The common analgesic paracetamol enhances the anti-tumour activity of decitabine through exacerbation of oxidative stress
H. J. Gleneadie, A. H. Baker, N. Batis, J. Bryant, Y. Jiang, S. J. Clokie, H. Mehanna, P. Garcia, D. M. Gendoo, S. Roberts, A. Molinolo, S. Gutkind, B. A. Scheven, P. R. Cooper, F. Khanim, M. Wiench
This study shows that paracetamol enhances decitabine's anti-tumour effects by increasing oxidative stress without worsening DNA damage.
bioRxiv · Mar 31, 2020 · PreprintCancer Biology