The hyperlipidaemic drug fenofibrate significantly reduces infection by SARS-CoV-2 in cell culture models
S. P. Davies, C. J. Mycroft-West, I. Pagani, H. J. Hill, Y.-H. Chen, R. T. Karlsson, I. Bagdonaite, S. E. Guimond, Z. Stamataki, M. A. Lima, J. E. Turnbull, Z. Yang, E. E. Vicenzi, M. A. Skidmore, F. Khanim, A. Richardson
This study shows fenofibrate and its metabolite fenofibric acid reduce SARS-CoV-2 infection in cell culture by up to 70% at clinically achievable concentrations.
bioRxiv · Jan 10, 2021Pharmacology & Toxicology