TCR Repertoire Analysis of CD4-Positive T Cells from Blood and an Affected Organ in an Autoimmune Mouse Model
T. Ishikawa, K. Horie, Y. Takakura, H. Ohki, Y. Maruyama, M. Hayama, M. Miyauchi, T. Miyao, N. Hagiwara, T. J. Kobayashi, N. Akiyama, T. Akiyama
This study examines TCR repertoires in CD4+ T cells from blood and stomachs of AIRE KO mice to correlate TCR diversity with autoimmune symptom variation and organ-specific disease manifestations.
bioRxiv · Mar 8, 2023 · PreprintImmunology