T. Seki

Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity

This study identifies C15ORF48 as a mitochondrial protein that induces stress-independent autophagy, reducing oxidative stress and autoimmunity in thymic epithelial cells.

Analysis of IGHA1 and other salivary proteins post half marathon in female participants

This study examines changes in salivary proteins, including IGHA1, in female participants before and after a half marathon, finding suppressed antimicrobial proteins and positive correlations among stress markers.

PEGPH20, a PEGylated Human Hyaluronidase, Induces Radiosensitization by Reoxygenation In Pancreatic Cancer Xenografts. A Molecular Imaging Study

This study shows PEGPH20 improves radiation therapy efficacy in pancreatic cancer tumors with high hyaluronan by increasing oxygenation, as measured by multiple imaging techniques.

Integrative analysis of scRNAs-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator

The paper identifies transit-amplifying thymic epithelial cells expressing Aire and CD80 through integrative scRNA-seq and scATAC-seq analysis.

Water uptake analysis in Japanese mustard spinach: A numerical approach

This study measures water uptake dynamics in Japanese mustard spinach using an experimental system and image analysis, revealing turgor movement through frequency domain analysis.

Transcriptome stability profiling identifies novel and functional MIRNA targets in melanoma cells

The paper uses RNA stability profiling to identify novel miR-211 targets in melanoma cells and validates their functional role in cell invasion and colony formation.

Distinguishing Closely Related Pancreatic Cancer Subtypes In Vivo by 13C Glucose MRI without Hyperpolarization

The paper distinguishes closely related pancreatic cancer subtypes in vivo using 13C glucose MRI without hyperpolarization by detecting metabolic differences through tensor decomposition.