Author

Y. Takakura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

K. Horie· 3 shared M. Hayama· 3 shared M. Miyauchi· 3 shared N. Akiyama· 3 shared T. Akiyama· 3 shared T. Ishikawa· 3 shared T. Miyao· 3 shared Y. Maruyama· 3 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

K. Horie

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Author profile →

3 papers

Recent·Most cited

Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity

Y. Takakura, M. Machida, N. Terada, Y. Katsumi, S. Kawamura, K. Horie, M. Miyauchi, T. Ishikawa, N. Akiyama, T. Seki, T. Miyao, M. Hayama, R. Endo, H. Ishii, Y. Maruyama, , N. Yamaguchi

This study identifies C15ORF48 as a mitochondrial protein that induces stress-independent autophagy, reducing oxidative stress and autoimmunity in thymic epithelial cells.

bioRxiv · Oct 17, 2023Cell Biology

TCR Repertoire Analysis of CD4-Positive T Cells from Blood and an Affected Organ in an Autoimmune Mouse Model

T. Ishikawa, K. Horie, Y. Takakura, H. Ohki, Y. Maruyama, M. Hayama, M. Miyauchi, T. Miyao, N. Hagiwara, T. J. Kobayashi, N. Akiyama, T. Akiyama

This study examines TCR repertoires in CD4+ T cells from blood and stomachs of AIRE KO mice to correlate TCR diversity with autoimmune symptom variation and organ-specific disease manifestations.

bioRxiv · Mar 8, 2023 · PreprintImmunology

Integrative analysis of scRNAs-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator

T. Akiyama, T. MIyao, M. Miyauchi, T. Kelly, T. W. Terooatea, T. Ishikawa, E. Oh, S. Hirai, K. Horie, Y. Takakura, H. Ohki, M. Hayama, Y. Maruyama, T. Seki, H. Yabukami, , N. Akiyama

The paper identifies transit-amplifying thymic epithelial cells expressing Aire and CD80 through integrative scRNA-seq and scATAC-seq analysis.

bioRxiv · Oct 4, 2021Immunology