Author

S. E. Harding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biophysics· 1 Cell Biology· 1 Physiology· 1

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Assay:imaging· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2

Frequent Co-Authors

N. Rosenthal· 3 shared S. Sattler· 3 shared J. Branca· 2 shared M. G. Hasham· 2 shared A. B. Herr· 1 shared A. E. Yarawsky· 1 shared A. Lota· 1 shared A. Papanikolaou· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersImmunology

N. Rosenthal

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Author profile →

6 papers

Recent·Most cited

Remote-refocusing light-sheet fluorescence microscopy enables 3D imaging of electromechanical coupling of hiPSC-derived and adult cardiomyocytes in co-culture

L. Dvinskikh, H. Sparks, L. Brito, K. T. MacLeod, S. E. Harding, C. Dunsby

This study uses remote-refocusing light-sheet microscopy to image electromechanical coupling in co-cultured adult and hiPSC-derived cardiomyocytes, showing improved coupling over time.

bioRxiv · Jan 28, 2023Cell Biology

Strong non-ideality effects at low protein concentrations: considerations for elongated proteins

A. E. Yarawsky, V. Dinu, S. E. Harding, A. B. Herr

The paper investigates non-ideal behavior in extended proteins at low concentrations using SEC, AUC, and viscosity measurements, finding significant hydrodynamic non-ideality in Brpt5.5 and Brpt1.5 compared to BSA.

bioRxiv · Dec 22, 2022Biophysics

Myocardial damage induced by a single high dose of isoproterenol in C57BL/6J mice triggers a persistent adaptive immune response against the heart.

E. Forte, M. Panahi, F. S. Ng, J. J. Boyle, J. Branca, O. Bedard, M. G. Hasham, L. Benson, S. E. Harding, N. Rosenthal, S. Sattler

This study shows that a single high dose of isoproterenol in mice causes myocardial damage and a persistent adaptive immune response against the heart, making it a suitable model for studying anti-heart autoimmunity.

bioRxiv · Feb 27, 2020Immunology

Persistent anti-heart autoimmunity causes cardiomyocyte damage in chronic heart failure.

A. Sintou, S. el Rifai, C. Mansfield, S. Rothery, J. L. Sanchez Alonso, S. Narodden, K. Sharma, E. Ferraro, M. G. Hasham, P. Swiatlowska, S. E. Harding, N. Rosenthal, J. Gorelik, S. Sattler

This study shows that persistent anti-heart autoimmunity contributes to cardiomyocyte damage and chronic heart failure progression in rats after myocardial infarction.

bioRxiv · Mar 13, 2019Immunology

Detection of acute TLR-7 agonist-induced hemorrhagic myocarditis in mice by refined multi-parametric quantitative cardiac MRI.

N. Baxan, A. Papanikolaou, I. Salles-Crawley, A. Lota, R. Chowdhury, O. Dubois, J. Branca, M. Hasham, N. Rosenthal, S. Prasad, L. Zhao, S. E. Harding, S. Sattler

This study identifies hemorrhagic myocarditis in mice induced by TLR-7 agonist using multi-parametric cardiac MRI, showing distinct T1, T2, and T2* relaxation patterns.

bioRxiv · Dec 21, 2018Physiology

Overexpression Of Hypoxia-Inducible Factor 1 Alpha Improves Immunomodulation By Dental Mesenchymal Stem Cells

V. G. Martinez, I. Ontoria-Oviedo, C. P. Ricardo, S. E. Harding, R. Sacedon, A. Varas, A. Zapata, P. Sepulveda, A. Vicente

This study shows that overexpressing HIF-1 alpha in dental mesenchymal stem cells enhances their immunomodulatory abilities and resistance to NK cell lysis, improving their therapeutic potential.

bioRxiv · May 24, 2017Immunology