Author

H. Tsugawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

H. Suzuki· 1 shared H. Takeda· 1 shared H. Yamamoto· 1 shared J. Matsuzaki· 1 shared J. Miyamoto· 1 shared K. Hozumi· 1 shared K. Oobuchi· 1 shared K. Sasaki· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

H. Suzuki

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Using variable data independent acquisition for capillary electrophoresis-based untargeted metabolomics

S. Kiuchi, Y. Otoguro, T. Nitta, M. H. Chung, T. Nakaya, K. Oobuchi, K. Sasaki, H. Yamamoto, H. Tsugawa

This study evaluates DIA techniques for CE-MS/MS metabolomics, showing vDIA with MS-DIAL improves annotation rates and accuracy, and identifies new metabolites in LPS-treated macrophages.

Journal of the American Society for Mass Spectrometry · Aug 13, 2024Peer-reviewedBiochemistry

A procedure for solid phase extractions using metal oxide coated silica column in lipidomics

H. Takeda, M. Takeuchi, M. Hasegawa, J. Miyamoto, H. Tsugawa

The paper introduces a solid-phase extraction method using metal oxide-coated silica columns to fractionate lipids into neutral, phospholipids, and other lipid classes for lipidomics.

bioRxiv · Oct 15, 2023Bioengineering

Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver

H. Tsugawa, T. Ohki, S. Tsubaki, R. Tanaka, J. Matsuzaki, H. Suzuki, K. Hozumi

This study shows that Gas6, secreted by intestinal macrophages, prevents K. pneumoniae translocation to the liver in mice, but its reduction in aging allows bacterial invasion and systemic infection.

bioRxiv · Jan 19, 2023Microbiology