Author

H. Y. Mak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

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Organism:C. elegans· 5 Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 4 Assay:proteomics· 4 Research Focus:development & morphogenesis· 3 Assay:bulk RNA-seq· 2 Assay:electronic health records· 1

Frequent Co-Authors

X. Li· 4 shared J. Qu· 3 shared K. Xie· 2 shared N. Xu· 2 shared P. Liu· 2 shared Z. Cao· 2 shared B.-H. Kang· 1 shared C. B. Preusch· 1 shared

Activity by Year

2018-2022 · peak 2/yr

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10 top collaborators · 25 mutual co-author links

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4 shared papersCell Biology

X. Li

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5 papers

Recent·Most cited

A flexible network of lipid droplet associated proteins support embryonic integrity of C. elegans

Z. Cao, C. W. Fung, H. Y. Mak

The paper investigates the role of lipid droplet-associated proteins in C. elegans embryonic development, finding that SEIP-1 and other proteins redundantly support lipid barrier formation and embryonic survival.

bioRxiv · Jan 30, 2022Cell Biology

The endoplasmic reticulum-resident protein TMEM-120/TMEM120A promotes fat storage in C. elegans and mammalian cells

Y. Li, S. Huang, X. Li, X. Yang, N. Xu, J. Qu, H. Y. Mak

This study identifies TMEM-120/TMEM120A as a conserved protein that promotes fat storage by enhancing triacylglycerol synthesis and lipid droplet expansion in C. elegans and mammalian cells.

bioRxiv · Jun 29, 2021 · PreprintCell Biology

Nuclear receptor NHR-49 promotes peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans

L. Zeng, X. Li, C. B. Preusch, G. J. He, N. Xu, T. H. Cheung, J. Qu, H. Y. Mak

The paper shows that NHR-49 promotes peroxisome proliferation in C. elegans to compensate for ALH-4 deficiency, which leads to elevated fatty aldehydes and reduced fat storage.

bioRxiv · Dec 4, 2020Cell Biology

Dietary S. maltophilia promotes fat storage by enhancing lipogenesis and ER-LD contacts in C. elegans

K. Xie, Y. Liu, X. Li, H. Zhang, S. Zhang, H. Y. Mak, P. Liu

bioRxiv · Apr 29, 2020 · PreprintCell Biology

Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

Z. Cao, Y. Hao, Y. Y. Lee, P. Wang, X. Li, K. Xie, W. J. Lam, Y. Qiu, G. Shui, P. Liu, J. Qu, B.-H. Kang, H. Y. Mak

The paper shows dietary fatty acids influence lipid droplet diversity via SEIP-1 enrichment in an ER subdomain in C. elegans and mammalian cells.

bioRxiv · Sep 22, 2018Cell Biology