Y.-C. Yang

Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma

This study evaluates the therapeutic potential of RMC-7977, a broad-spectrum RAS inhibitor, in pancreatic ductal adenocarcinoma models, showing strong anti-tumor effects with minimal impact on normal tissues.

Effective buprenorphine use and tapering strategies: Endorsements and insights by people in recovery from opioid use disorder on a Reddit forum

This study analyzes Reddit posts to identify buprenorphine use and tapering strategies reported by people in recovery from opioid use disorder, finding that longer tapering schedules may lead to sustained recovery.

Reducing expression of dynamin-related protein 1 increases radiation sensitivity of glioblastoma cells

This study shows that reducing DRP1 expression increases radiation sensitivity of glioblastoma cells by inhibiting DNA repair and enhancing drug uptake.

TAO Kinase 3 Overexpression Is a Poor Prognosis Marker for Lung Adenocarcinoma and Predicts Paclitaxel Resistance

This study shows TAOK3 overexpression correlates with poor prognosis and paclitaxel resistance in lung adenocarcinoma, suggesting it as a therapeutic target.

Circular RNAs regulate cancer stem cells by FMRP against CCAR1 complex in hepatocellular carcinoma

This study identifies circZKSCAN1 as a negative regulator of cancer stem cells in hepatocellular carcinoma, revealing its mechanism through interaction with FMRP and CCAR1-Wnt signaling.

Naa10p promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas

This study shows Naa10p promotes osteosarcoma metastasis by stabilizing MMP-2 protein through N-terminal acetylation.