Author

H.-H. Ling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

H. Chen· 2 shared A. D. Viny· 1 shared D. Kumar· 1 shared E. Caggiano· 1 shared F. G. Giancotti· 1 shared F. Giancotti· 1 shared J. Zhang· 1 shared R. A. DePinho· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

H. Chen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mediator Subunit Med4 Enforces Metastatic Dormancy in Breast Cancer

S.-Y. Bae, H.-H. Ling, Y. Chen, H. Chen, D. Kumar, J. Zhang, A. D. Viny, R. A. DePinho, F. G. Giancotti

This study identifies Med4 as a regulator of metastatic dormancy in breast cancer, showing its role in maintaining chromatin structure and suppressing enhancer activation.

bioRxiv · Nov 18, 2023Cancer Biology

SARS-CoV-2 Exploits Sexually Dimorphic and Adaptive IFN and TNFa Signaling to Gain Entry into Alveolar Epithelium

F. Giancotti, Y. Wang, S. Gurrapu, H. Chen, S. Laudato, E. Caggiano, Y. Jiang, H.-H. Ling

This study shows SARS-CoV-2 exploits sex-specific IFN and TNFα signaling to enhance ACE2 and TMPRSS2 expression in male alveolar cells, promoting viral entry and suggesting potential therapeutic targets.

bioRxiv · Jul 23, 2021 · PreprintImmunology