Haley S. Province

GIP receptor agonism suppresses inflammation-induced aversion and food intake via distinct circuits

This study shows that GIP receptor agonism reduces food intake and prevents aversion through distinct neural circuits, with different roles for CGRP neurons and the dorsal vagal complex.

IL-1β engages distinct peripheral sensory circuits to suppress feeding across time

This study identifies two distinct phases of IL-1β-induced anorexia mediated by different peripheral sensory circuits.

Sequence termination cues drive habits via dopamine-mediated credit assignment

This study shows that sequence termination cues, via dopamine signaling, drive habitual behavior by enhancing automaticity and reducing behavioral flexibility.

Sucrose overconsumption impairs feeding circuit dynamics and promotes palatable food intake

This study shows that high-sucrose diets impair gut-brain communication by altering AgRP neuron activity, leading to increased palatable food intake.

Preoptic BRS3 neurons increase body temperature and heart rate via multiple pathways

The paper identifies POA BRS3 neurons that increase body temperature and heart rate through multiple pathways, revealing their role in thermoregulation and cardiovascular control.