Author
Northwestern University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Hayley E. McMorrow, Carolyn M. Lorch, Nikolas W. Hayes, Stefan W. Fleps, Joshua A. Frydman, Jessica L. Xia, Ricardo J. Samms, Lisa R. Beutler
This study shows that incretin hormone analogs inhibit AgRP neuron activity to suppress appetite, with GIP playing a unique role in nutrient-mediated inhibition.
bioRxiv · Mar 18, 2024 · PreprintNeuroscience
Carolyn M. Lorch, Nikolas W. Hayes, Jessica L. Xia, Stefan W. Fleps, Hayley E. McMorrow, Haley S. Province, Joshua A. Frydman, Jones G. Parker, Lisa R. Beutler
This study shows that high-sucrose diets impair gut-brain communication by altering AgRP neuron activity, leading to increased palatable food intake.
Cell Reports · Jan 14, 2024Peer-reviewedNeuroscience
Seongsik Yun, Ben Yang, Justin D. Anair, Madison M. Martin, Stefan W. Fleps, Arin Pamukcu, Nai-Hsing Yeh, Anis Contractor, Ann Kennedy, Jones G. Parker
The paper investigates the neural mechanisms of antipsychotic drugs by comparing their effects on D1- and D2-receptor-expressing spiny-projection neurons in mice, finding that modulating D1-SPNs correlates with therapeutic efficacy.
Nature Neuroscience · Jul 13, 2023Peer-reviewedNeuroscience
Nicolette A. Moya, Seongsik Yun, Stefan W. Fleps, Madison M. Martin, Jacob A. Nadel, Lisa R. Beutler, Larry S. Zweifel, Jones G. Parker
This study shows that selectively increasing dopamine in the dorsal striatum impairs behaviors linked to negative and cognitive symptoms of psychosis, challenging the idea that excess dopamine is not involved in these symptoms.
Neuropsychopharmacology · Nov 15, 2022Peer-reviewedNeuroscience