Author
Harvard University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Zhenguang Zhao, Wenqing Xu, Ethan Yang Feng, Shiyun Cao, Alba Hermoso-López, Pablo Peña-Vega, Hannah C. Lloyd, Abigail K. D. Porter, Manuel Guzmán, Ning Zheng, Christina M. Woo
The paper identifies PCMT1 as an enzyme that forms C-terminal cyclic imides on CRBN substrates, linking it to metabolic enzyme regulation and epileptic phenotypes.
Nature Chemical Biology · Dec 29, 2025Peer-reviewedBiochemistry
Hannah C. Lloyd, Yuli Li, N. Connor Payne, Zhenguang Zhao, Wenqing Xu, Alena Kroupova, David Zollman, Tengfang Long, Farah Kabir, Mei Chen, Rebecca J. Freeman, Ethan Yang Feng, Sarah Y Xi, Ya-Chieh Hsu, Alessio Ciulli, , Christina M. Woo
This paper introduces a method called cerebody to detect and enrich endogenous cereblon substrates by targeting C-terminal cyclic imide modifications.
Cell Chemical Biology · Aug 1, 2025Peer-reviewedBiochemistry
Wenqing Xu, Zhenguang Zhao, Matthew Su, Atul D. Jain, Hannah C. Lloyd, Ethan Yang Feng, Nick Cox, Christina M. Woo
The paper investigates C-terminal cyclic imides as protein damage products, their formation mechanisms, and their impact on protein stability and quality control via CRBN.
Proceedings of the National Academy of Sciences · Dec 30, 2024Peer-reviewedBiochemistry