A method for the detection and enrichment of endogenous cereblon substrates
Hannah C. Lloyd, Yuli Li, N. Connor Payne, Zhenguang Zhao, Wenqing Xu, Alena Kroupova, David Zollman, Tengfang Long, Farah Kabir, Mei Chen, Rebecca J. Freeman, Ethan Yang Feng, Sarah Y Xi, Ya-Chieh Hsu, Alessio Ciulli, , Christina M. Woo
This paper introduces a method called cerebody to detect and enrich endogenous cereblon substrates by targeting C-terminal cyclic imide modifications.
Cell Chemical Biology · Aug 1, 2025Peer-reviewedBiochemistry