Breaking the cycle: How targeting CD44v6/MET signaling disrupts colorectal cancer cell plasticity
Steffen Joachim Sonnentag, Selina Goldbach, Dominique Hoch, Geoffroy Andrieux, Jonas Philipp Becker, hannah Fromm, L. Munoz-Sagredo, Yvonne M. Heneka, Dirk Grimm, Florian R. Greten, Véronique Orian‐Rousseau
This study shows that targeting CD44v6/MET signaling disrupts colorectal cancer cell plasticity by repressing Lgr5+ cell reappearance and affecting YAP/TAZ signaling.
bioRxiv · Sep 27, 2024 · PreprintCancer Biology