Author

Dominique Hoch

Karlsruhe Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Geoffroy AndrieuxiD· 2 shared Steffen Joachim SonnentagiD· 2 shared Véronique Orian‐RousseauiD· 2 shared Yvonne M. HenekaiD· 2 shared Alessandra GarganoiD· 1 shared Dirk GrimmiD· 1 shared Eliana StanganelloiD· 1 shared Florian R. GreteniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Geoffroy AndrieuxORCID

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2 papers

Recent·Most cited

Loss of CD44 re-educates pancreatic cancer-associated fibroblasts modulating their fibrotic and immunosuppressive functions

Sven Máté Treffert, Yvonne M. Heneka, Julie Martin, Alessandra Gargano, Larissa Launhardt, Özlem Akilli‐Öztürk, Eliana Stanganello, Geoffroy Andrieux, Dominique Hoch, Steffen Joachim Sonnentag, Lisa-Marie Mehner, Leonel Muñoz‐Sagredo, Michelle Christ, Véronique Orian‐Rousseau

This study shows that CD44 deletion in pancreatic cancer-associated fibroblasts reduces tumor volume, alters their morphology and function, and enhances anti-tumor immune responses.

Cell Death and Disease · Aug 15, 2026Peer-reviewedCancer Biology

Breaking the cycle: How targeting CD44v6/MET signaling disrupts colorectal cancer cell plasticity

Steffen Joachim Sonnentag, Selina Goldbach, Dominique Hoch, Geoffroy Andrieux, Jonas Philipp Becker, hannah Fromm, L. Munoz-Sagredo, Yvonne M. Heneka, Dirk Grimm, Florian R. Greten, Véronique Orian‐Rousseau

This study shows that targeting CD44v6/MET signaling disrupts colorectal cancer cell plasticity by repressing Lgr5+ cell reappearance and affecting YAP/TAZ signaling.

bioRxiv · Sep 27, 2024 · PreprintCancer Biology