A Novel Stress Response Pathway Mediates Antibiotic Tolerance and Architecture in Pseudomonas aeruginosa Biofilms
Ainelén Piazza, Catriona M. A. Thompson, Govind Chandra, Harshanie Dasanayaka, Gerhard Saalbach, Carlo Martins, Eleftheria Trampari, Mark Alexander Webber, Freya Harrison, Jacob G. Malone
This study identifies BatR as a regulator of biofilm formation and antibiotic tolerance in Pseudomonas aeruginosa, showing its interaction with SrkA and role in eDNA release and pyocyanin production.
bioRxiv · Dec 22, 2025 · PreprintMicrobiology