Gerhard Saalbach

Conservation and evolution of the ribosome across the photosynthetic lineage

The paper examines changes in chloroplast ribosomes during evolution from cyanobacteria to land plants, identifying structural features and protein modifications.

Defining the OrrA regulon and its role in development and antibiotic production in Streptomyces venezuelae NRRL B-65442

This study defines the OrrA regulon in Streptomyces venezuelae, showing it regulates sporulation and antibiotic production via WblA.

MtrAB activates ectoine production and triggers sporulation in response to osmotic stress in Streptomyces venezuelae

This paper shows that MtrAB in Streptomyces venezuelae senses osmotic stress via sucrose, activates ectoine production, and triggers sporulation through direct regulation of bldM and whiI.

A Novel Stress Response Pathway Mediates Antibiotic Tolerance and Architecture in Pseudomonas aeruginosa Biofilms

This study identifies BatR as a regulator of biofilm formation and antibiotic tolerance in Pseudomonas aeruginosa, showing its interaction with SrkA and role in eDNA release and pyocyanin production.

Extracellular Vesicle-Linked Vitamin B12 Acquisition via Novel Binding Proteins in Bacteroides thetaiotaomicron

This study identifies novel cobalamin-binding proteins in Bacteroides thetaiotaomicron and shows their role in extracellular vesicle-mediated nutrient acquisition.

Redox control of antibiotic biosynthesis

The paper investigates redox control of antibiotic biosynthesis in Streptomyces formicae, showing that a redox-sensitive repressor senses oxygen to regulate formicamycin production.

The conserved two-component systems CutRS and CssRS control the protein secretion stress response in Streptomyces species

This paper identifies CutRS as a two-component system in Streptomyces that senses secretion stress via cysteine residues and regulates antibiotic production in response to glucose.

Three cytochrome P450 enzymes catalyse the formation of furanoclerodane precursors in Salvia spp.

The paper identifies three cytochrome P450 enzymes involved in furanoclerodane biosynthesis in Salvia splendens and supports their evolutionary link to salvinorin A biosynthesis in S. divinorum.

The conserved aphid saliva chemosensory protein effector Mp10 targets plant AMSH deubiquitinases at cellular membranes to suppress pattern-triggered immunity

This study identifies Mp10, an aphid saliva CSP effector, which suppresses plant PTI by interacting with AMSH deubiquitinases and modulating PRR kinase trafficking.

Within-ejaculate sperm selection in humans acts against molecular signatures of age-related disease

The paper identifies within-ejaculate sperm selection in humans that favors sperm with molecular signatures opposing age-related disease.

A CPF-like phosphatase module links transcription termination to chromatin silencing

This paper shows how transcription termination via the CPF-like phosphatase module affects chromatin silencing of FLC in Arabidopsis, influencing flowering time.

BatR: A novel regulator of antibiotic tolerance in Pseudomonas aeruginosa biofilms

This study identifies PA3049, renamed BatR, as a key regulator of antibiotic tolerance in Pseudomonas aeruginosa biofilms, showing its role in stress response and antimicrobial resistance.