Author

Hilena Gebre

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ralda NehmeiD· 2 shared Aditi Trehan· 1 shared Agnete KirkebyiD· 1 shared August Benjamin SmitiD· 1 shared Daniel MeyeriD· 1 shared Danzel Rebelo· 1 shared Daya MenaiD· 1 shared Derek Hawes· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Ralda NehmeORCID

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2 papers

Recent·Most cited

A foundational neuronal protein network model unifying multimodal genetic, transcriptional, and proteomic perturbations in schizophrenia.

Greta Pintacuda, Yu-Han H. Hsu, Petra Páleníková, Ugne Dubonyte, Nadine Fornelos, Miao Chen, Daya Mena, Julia C. Biagini, Travis Botts, Makayla Martorana, Danzel Rebelo, Joshua Ching, Ethan Crouse, Hilena Gebre, Xian Adiconis, , Kasper Lage

The paper identifies three neuron-specific schizophrenia protein networks enriched for genetic and transcriptional perturbations and validates their disruption in 22q11.2 deletion carriers.

medRxiv · May 2, 2025 · PreprintGenetic & Genomic Medicine

Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons

Olli P. H. Pietiläinen, Aditi Trehan, Daniel Meyer, Jana M. Mitchell, Matthew Tegtmeyer, Vera Valakh, Hilena Gebre, Theresa Chen, Emilia Vartiainen, Samouil L. Farhi, Kevin C. Eggan, Steven A. McCarroll, Ralda Nehme

The paper shows that astrocyte-neuron interactions enhance synaptic gene expression in neurons and correlate with schizophrenia risk genes.

Cell Reports · Jan 1, 2023Peer-reviewedMolecular Biology