Author

Hoi Man Chung

University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Research Focus:clustering· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Yuanhua HuangiD· 3 shared Christopher J. JollyiD· 2 shared Fabio ZaniniiD· 2 shared Fatemeh VafaeeiD· 2 shared Feng YaniD· 2 shared Forrest C. KochiD· 2 shared Henry R. HamptoniD· 2 shared John E. PimandaiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Yuanhua HuangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell-state-specific mechanisms of 5-azacytidine response in myelodysplastic neoplasms

Golam Sarower Bhuyan, Feng Yan, Mary N.T. Nguyen, Hoi Man Chung, Xiaoheng Zou, Veena Gullapalli, Lachlin Vaughan, Olivia J. Stonehouse, Henry R. Hampton, Shen Sylvie, Peter Truong, Ruchira Kumari DİSSANAYAKE, Elaheh Sadat Ghodousi, Swapna Joshi, Forrest C. Koch, , John E. Pimanda

The paper identifies cell-state-specific mechanisms of 5-azacytidine response in myelodysplastic neoplasms, showing distinct differentiation and transcriptional changes in cycling progenitors and quiescent stem cells.

bioRxiv · Jul 20, 2026 · PreprintCancer Biology

Single cell multiomics reveal clonal and functional dynamics of MDS stem/progenitor cells during hypomethylating therapy

Julie A.I. Thoms, Henry R. Hampton, Priscilla Li Shan Boon, Olivia J. Stonehouse, Xiaoheng Zou, Hoi Man Chung, Forrest C. Koch, Feng Yan, Swapna Mahurkar Joshi, Mary N.T. Nguyen, Dorothy Hung, Dale Cameron Wright, Fatemeh Vafaee, Mark Niccolo Polizzotto, Alexander Swarbrick, , John E. Pimanda

This study uses single-cell multiomics to show that AZA response in MDS involves hematopoietic regeneration from mutated HSPCs and that AZA-refractive sub-populations contribute to disease progression.

bioRxiv · Mar 13, 2026 · PreprintCancer Biology

Interpretable variational encoding of genotypes identifiescomprehensive clonality and lineages in single cells geometrically

Hoi Man Chung, Yuanhua Huang

SNPmanifold uses a variational autoencoder to identify clonality and lineages in single cells, outperforming existing methods in complex datasets.

bioRxiv · Jul 4, 2024 · PreprintGenomics