Author

Mark Niccolo Polizzotto

Australian National UniversityORCID 0000-0002-6446-183XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christopher J. JollyiD· 2 shared Feng YaniD· 2 shared Henry R. HamptoniD· 2 shared John E. PimandaiD· 2 shared Julie A.I. ThomsiD· 2 shared Mary N.T. NguyeniD· 2 shared Alexander SwarbrickiD· 1 shared Anne PaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Christopher J. JollyORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Azacitidine Response in Myelodysplastic Syndromes is Marked by NK-like CD8 T-Cell Expansion and CXCL12+ Reticular Cell Remodeling

Henry R. Hampton, Anne Pan, Michael J. Carnell, Bofei Wang, Diana Shinko, Maria A. Kasherman, Iveta Šlapetová, Swapna Joshi, Mary N.T. Nguyen, Feng Yan, Sarah Davidson, Nick F.Y. Choi, Jason W.H. Wong, Nicodemus T. Tedla, Devendra Hiwase, , John E. Pimanda

The paper identifies NK-like CD8 T-cell expansion and CXCL12+ reticular cell remodeling as markers of azacitidine response in MDS through longitudinal bone marrow profiling.

bioRxiv · Jul 8, 2026 · PreprintCancer Biology

Single cell multiomics reveal clonal and functional dynamics of MDS stem/progenitor cells during hypomethylating therapy

Julie A.I. Thoms, Henry R. Hampton, Priscilla Li Shan Boon, Olivia J. Stonehouse, Xiaoheng Zou, Hoi Man Chung, Forrest C. Koch, Feng Yan, Swapna Mahurkar Joshi, Mary N.T. Nguyen, Dorothy Hung, Dale Cameron Wright, Fatemeh Vafaee, Mark Niccolo Polizzotto, Alexander Swarbrick, , John E. Pimanda

This study uses single-cell multiomics to show that AZA response in MDS involves hematopoietic regeneration from mutated HSPCs and that AZA-refractive sub-populations contribute to disease progression.

bioRxiv · Mar 13, 2026 · PreprintCancer Biology