Sigma-1 Receptor Promotes Glycolysis in Neuronal Systems by Suppressing GRIM19
Simon Couly, Yuko Yasui, Ioannis Grammatikakis, Yuriko Kimura, Josh. J. Hinkle, Juan L. Gomez, Hsiang-En Wu, Ghosh Paritosh, Ashish Lal, Michael Michaelides, Brandon K. Harvey, Tsung‐Ping Su
This study shows that Sigma-1 receptor promotes glycolysis in neuronal systems by suppressing GRIM19, affecting NAD+/NADH metabolism and mitochondrial activity.
iScience · May 26, 2026Peer-reviewedCell Biology