Author
National Institute on Drug AbuseORCID 0000-0003-3170-9904Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Simon Couly, Yuko Yasui, Ioannis Grammatikakis…·Tsung‐Ping Su
This study shows that Sigma-1 receptor promotes glycolysis in neuronal systems by suppressing GRIM19, affecting NAD+/NADH metabolism and mitochondrial activity.
Ginevra D’Ottavio, Alana Sullivan, Emma M. Pilz…·Yavin Shaham
This study identifies neurometabolic differences in rats associated with heroin addiction vulnerability and social seeking using FDG-PET imaging and behavioral assays.
Shannan P. McClain, Xiang Ma, Desiree A. Johnson…·Matthew R. Banghart
This paper introduces photoactivatable opioid drugs for in vivo photopharmacology, enabling rapid, localized manipulation of opioid receptors and associated behaviors.
Jennifer M. Bossert, Carlos A. Mejías-Aponte, Thomas L. Saunders…·Yavin Shaham
This study introduces a CRISPR-based Oprm1-Cre knock-in rat to investigate the role of nucleus accumbens MOR-expressing cells in heroin self-administration, finding sex-specific effects on acquisition and effort.
Juan L. Gomez, Jordi Bonaventura, Jacqueline D. Keighron…·Michael Michaelides
This study shows that synaptic Zn2+ enhances cocaine's effects on striatal dopamine neurotransmission and behavior by increasing DAT binding and altering locomotor responses.
Jordi Bonaventura, Mark A. G. Eldridge, Feng Hu…·Michael Michaelides
The paper develops new DREADD agonists and a PET radiotracer for improved neuronal activity manipulation and noninvasive projection mapping in neurotheranostics.