Author

Simon Couly

National Institutes of HealthORCID 0000-0003-2248-1151Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Ashish LaliD· 2 shared Ioannis GrammatikakisiD· 2 shared Brandon K. HarveyiD· 1 shared Bruna Rodrigues MuysiD· 1 shared Erica C. PehrssoniD· 1 shared Ghosh ParitoshiD· 1 shared Hsiang-En Wu· 1 shared Josh. J. Hinkle· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Ashish LalORCID

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2 papers

Recent·Most cited

Cell BiologyiSciencePeer-reviewedMay 26, 2026

Sigma-1 Receptor Promotes Glycolysis in Neuronal Systems by Suppressing GRIM19

Simon Couly, Yuko Yasui, Ioannis Grammatikakis…·Tsung‐Ping Su

This study shows that Sigma-1 receptor promotes glycolysis in neuronal systems by suppressing GRIM19, affecting NAD+/NADH metabolism and mitochondrial activity.

DOI 10.1016/j.isci.2026.116092

mousehuman

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Cancer BiologybioRxivPreprintMay 12, 2025

p53-induced RNA-binding protein ZMAT3 inhibits transcription of a hexokinase to suppress mitochondrial respiration

Ravi Kumar, Simon Couly, Bruna Rodrigues Muys…·Ashish Lal

This study identifies ZMAT3 as a regulator of HKDC1 transcription through JUN, suppressing mitochondrial respiration in colorectal cancer cells.

1 citation

humanproteomics

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