Author

Huiyanangel Chow

AstraZeneca (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ali MostafaiD· 1 shared Ana Maria MansillaiD· 1 shared Ana PaucarmaytaiD· 1 shared Anna HuntleyiD· 1 shared Bilal A. OmariD· 1 shared Carolina Mendoza-Topaz· 1 shared Christine Mione KieferiD· 1 shared Christine YouniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Ali MostafaORCID

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Author profile →

1 paper

Recent·Most cited

Mechanisms regulating combination effect of antibody-drug conjugates and cancer immunotherapy

Şehmus Tohumeken, Ali Mostafa, Rashmi Binjawadagi, Mimi Mai, Ana Paucarmayta, Ana Maria Mansilla, Christine Youn, E Sally Chang, Pooja Shah, Huiyanangel Chow, Wileashire Moulton, Xiaokang Luo, Kerlene Berwick Tam, Matthew Flynn, Leslie K. Wetzel, , Dmitry I. Gabrilovich

This paper investigates the mechanisms of ADC-immunotherapy combinations, finding that ADC-induced autophagy upregulates TNFR and M6PR, driving antitumor effects through TNF and granzyme B pathways.

bioRxiv · Jul 22, 2026 · PreprintImmunology