Dmitry I. Gabrilovich

The paper shows that hydroperoxy-phospholipids are necessary but insufficient for ferroptosis, requiring additional Fe-catalyzed processes and agents to complete the death program.

This paper investigates the mechanisms of ADC-immunotherapy combinations, finding that ADC-induced autophagy upregulates TNFR and M6PR, driving antitumor effects through TNF and granzyme B pathways.

This study shows TMEM33 limits progenitor-exhausted CD8+ T cells, enhances anti-tumor responses, and correlates with improved survival in melanoma patients.

This study shows that neutrophil extracellular traps (NETs) contribute to tumor resistance to anthracycline chemotherapy by binding the drugs and protecting cancer cells.