Author

Huw McCarthy

National Health and Medical Research Council

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:metagenomics· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Shandelle Caban· 2 shared Simon KeelyiD· 2 shared Alena L. PribyliD· 1 shared Andrea Rabellino· 1 shared Annika KruegeriD· 1 shared Areej S. Alsheikh-HussainiD· 1 shared Blake WillsiD· 1 shared Bozica Nyeverecz· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersImmunology

Shandelle Caban

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Author profile →

2 papers

Recent·Most cited

Microbiota Modulation Induces Elevated Duodenal Eosinophils Upon Gluten Exposure in Mice: Implications for Non-Coeliac Gluten Sensitivity

Jennifer C. Pryor, Emily C. Hoedt, Wai Sinn Soh, Sophie Fowler, Shandelle Caban, Kyra Minahan, Simonne K. Sherwin, Cheenie Nieva, Huw McCarthy, Jay Christopher Horvat, Kateleen E Hedley, Kerith Duncanson, Nicholas J. Talley, Grace L. Burns, Simon Keely

This study shows that antibiotic-induced microbiome modulation in mice alters immune responses to gluten, increasing duodenal eosinophils and activating epithelial γδ T-cells.

bioRxiv · Apr 22, 2025 · PreprintImmunology

A rational approach for the targeted discovery and characterisation of microbiome-derived therapeutics

Lutz Krause, Joel A. Boyd, Charlotte Vivian, Annika Krueger, Jeimy Johana Jimenez Loayza, Johanna K. Ljungberg, Joyce Zhou, Andrea Rabellino, Bozica Nyeverecz, Michael D. Nissen, Kaylyn D. Tousignant, Mareike Bongers, Martha M. Cooper, Donovan H. Parks, Areej S. Alsheikh-Hussain, , Páraic Ó Cuív

This paper identifies microbiome-derived therapeutics for IBD using a metagenome-guided approach, showing improved disease markers and safety in preclinical models.

bioRxiv · Oct 22, 2024 · PreprintMicrobiology