Mechanistic insight into the regulation of virulence factor type 1 pili in pathogenic E. coli by rhomboid protease GlpG
Jimmy Lu, Elena I Arutyunova, Bridgette Hartley, Jonas Wong, Hyunjae Chung, Lanny Buchan, Heather Armstrong, Sadhna Phanse, Howard S. Young, Eytan Wine, Mohan Babu, Justin Chun, Wael Elhenawy, Olivier Julien, M. Joanne Lemieux
This study shows GlpG protease is essential for type 1 pili assembly in E. coli, affecting biofilm formation and bacterial fitness.
bioRxiv · Sep 9, 2025 · PreprintBiochemistry