Olivier Julien

This paper develops a two-step synthesis method for covalent genetically-encoded libraries of peptide-derived macrocycles (cGELs) that enables the use of electrophiles with diverse reactivity by controlling reaction conditions.

This study identifies Siglec-G as a checkpoint receptor on B cells that limits germinal center (GC) response by modulating T cell help during positive selection.

This study identifies a metabolite from E. coli that suppresses tau aggregation in vitro and in live bacteria, suggesting its potential for modulating tauopathies.

This study shows MMP-2 and MMP-9 contribute to cisplatin-induced ototoxicity by cleaving RAB proteins, and inhibiting them improves hair cell survival.

This study shows GlpG protease is essential for type 1 pili assembly in E. coli, affecting biofilm formation and bacterial fitness.

The paper investigates CD36 interactome to identify multimolecular complexes involved in anti-angiogenic signaling through proximity biotinylation and functional assays.

The paper investigates how maternal immune dysregulation and dysbiosis affect offspring gut immune homeostasis and T1D development in NOD mice.

This study shows that human CD33 isoforms differentially affect microglial responses in Alzheimer's disease, with CD33m showing protective effects against amyloid-beta pathology.