Author

İrem Kaya

Ghent University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Arne ClaeysiD· 1 shared Bengt HallbergiD· 1 shared Elien HilgertiD· 1 shared Ellen SandersiD· 1 shared Frank SpelemaniD· 1 shared Jimmy Van den EyndeniD· 1 shared Jo Van DorpeiD· 1 shared Joachim Tetteh SiawiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Arne ClaeysORCID

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1 paper

Recent·Most cited

RUVBL1 and RUVBL2 are druggable MYCN regulators in neuroblastoma.

Joachim Tetteh Siaw, Arne Claeys, Wei‐Yun Lai, Marcus Borenäs, Elien Hilgert, Sarah-Lee Bekaert, Ellen Sanders, İrem Kaya, Jo Van Dorpe, Frank Speleman, Kaat Durinck, Bengt Hallberg, Ruth Helen Palmer, Jimmy Van den Eynden

This study identifies RUVBL1 and RUVBL2 as druggable regulators of MYCN in neuroblastoma, showing their inhibition reduces MYC signaling and induces cell cycle arrest and apoptosis.

iScience · Mar 5, 2026Peer-reviewedCancer Biology