Author

I. Campeotto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:rat· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

D. Quinkert· 3 shared S. J. Draper· 3 shared L. Barfod· 2 shared A. Diouf· 1 shared A. J. Birkett· 1 shared A. Lias· 1 shared A. M. Frank· 1 shared A. M. Lias· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

D. Quinkert

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP and its antibody response characterisation

S. Batra, F. Olmo, T. J. Ragan, A. M. Frank, M. Kaplan, C. Lancey, M. Assadipapari, C. Ying, W. B. Struwe, E. Hesketh, J. M. Kelly, L. Barfod, I. Campeotto

This study determines the 3D structures of TcPOP in open and closed conformations using cryo-EM and evaluates its immunogenicity through antibody responses in mice.

bioRxiv · Mar 26, 2024 · PreprintBiophysics

Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5

T. Harrison, N. Alam, B. Farrell, D. Quinkert, A. Lias, L. King, S. J. Draper, M. K. Higgins, I. Campeotto

This paper designs a malaria vaccine immunogen using structure-guided methods to present a single epitope from PfRH5, showing improved antibody response in rats compared to PfRH5 alone.

bioRxiv · Feb 29, 2024Immunology

Preclinical Development of a Stabilized RH5 Virus-Like Particle Vaccine that Induces Improved Anti-Malarial Antibodies

L. D. W. King, D. Pulido, J. R. Barrett, H. Davies, D. Quinkert, A. M. Lias, S. E. Silk, D. J. Pattinson, A. Diouf, B. G. Williams, K. McHugh, A. Rodrigues, C. A. Rigby, V. Strazza, J. Suurbaar, , S. J. Draper

This paper develops a stabilized RH5 VLP vaccine that induces improved anti-malarial antibodies compared to a soluble protein vaccine in preclinical studies.

bioRxiv · Jan 4, 2024Immunology

Structure of the cysteine-rich domain of Plasmodium falciparum P113 identifies the location of the RH5 binding site

I. Campeotto, F. Galaway, S. Mehmood, L. Barfod, D. Quinkert, V. Kotraiah, T. W. Phares, K. E. Wright, A. P. Snijders, S. J. Draper, M. Higgins, G. J. Wright

The paper determines the structure of the RH5-binding region of P113 and identifies the binding site, providing insights for malaria vaccine development.

mBio · Oct 27, 2020Peer-reviewedMicrobiology