Author

S. Mehmood

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:structural biology· 3 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. C. Pike· 1 shared A. Chu· 1 shared A. Mey· 1 shared A. P. Snijders· 1 shared A. Pandini· 1 shared A. Ramanathan· 1 shared A. Sajid· 1 shared B. G. Davis· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. C. Pike

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Author profile →

3 papers

Recent·Most cited

Structural dynamics of the β-coronavirus Mpro protease ligand binding sites

E. Cho, M. Rosa, R. Anjum, S. Mehmood, M. Soban, M. Mujtaba, K. Bux, S. C. Dantu, A. Pandini, J. Yin, H. Ma, A. Ramanathan, B. Islam, A. Mey, D. BHOWMIK, S. Haider

The paper compares ligand-binding sites of Mpro proteases from SARS-CoV2, SARS-CoV, and MERS-CoV using deep learning and Markov state models to assess structural dynamics and conservation.

bioRxiv · Mar 31, 2021 · PreprintBiophysics

Structure of the cysteine-rich domain of Plasmodium falciparum P113 identifies the location of the RH5 binding site

I. Campeotto, F. Galaway, S. Mehmood, L. Barfod, D. Quinkert, V. Kotraiah, T. W. Phares, K. E. Wright, A. P. Snijders, S. J. Draper, M. Higgins, G. J. Wright

The paper determines the structure of the RH5-binding region of P113 and identifies the binding site, providing insights for malaria vaccine development.

mBio · Oct 27, 2020Peer-reviewedMicrobiology

Structures of DPAGT1 explain glycosylation disease mechanisms and advance TB antibiotic design

Y. Y. Dong, H. Wang, A. C. Pike, S. J. Cochrane, S. Hamedzade, F. J. Wyszynsk, S. R. Bushell, S. F. Royer, D. A. Widdick, A. Sajid, H. I. Boshoff, R. Lucas, W.-M. Liu, S. S. Lee, T. Machida, , E. P. Carpenter

This paper determines the structures of DPAGT1 with substrates and inhibitors, revealing catalytic mechanisms and disease-causing mutations, and designs non-toxic antibiotics for tuberculosis.

bioRxiv · Apr 2, 2018Biochemistry