Author

I. Ebersberger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

B. Djahanschiri· 2 shared G. Di Venanzio· 2 shared M. F. Feldman· 2 shared N.-H. Le· 2 shared A. Espaillat· 1 shared A. Gubas· 1 shared A. Jain· 1 shared A. Kalousi· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

B. Djahanschiri

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Domain-architecture aware phylogenetic profiling indicates a functional diversification of type IVa pili in the nosocomial pathogen Acinetobacter baumannii

R. Iruegas, K. Pfefferle, S. Göttig, B. Averhoff, I. Ebersberger

This study uses domain-architecture aware phylogenetic profiling to show that type IVa pili in Acinetobacter baumannii have diversified in domain structure, contributing to virulence and host interaction differences.

bioRxiv · Feb 1, 2023 · PreprintMicrobiology

InvL, an invasin-like adhesin, is a type II secretion system substrate required for Acinetobacter baumannii uropathogenesis.

C. D. Jackson-Litteken, G. Di Venanzio, N.-H. Le, N. E. Scott, B. Djahanschiri, J. Distel, E. J. Pardue, I. Ebersberger, M. F. Feldman

This paper identifies InvL, a type II secretion system effector in Acinetobacter baumannii, as an adhesin required for urinary tract infection.

mBio · Jun 28, 2022Peer-reviewedMicrobiology

The evolutionary making of SARS-CoV-2

R. Iruegas Lopez, J. Dosch, M. Sikora, G. Hummer, R. Covino, I. Ebersberger

This study identifies evolutionary innovations in SARS-CoV-2 protein sequences, highlighting functional changes in the spike protein and its furin cleavage site relevant to immune evasion and infection.

bioRxiv · Jan 29, 2021 · PreprintEvolutionary Biology

Combinatorial CRISPR screening reveals functional buffering in autophagy

V. Diehl, M. Wegner, P. Grumati, K. Husnjak, S. Schaubeck, A. Gubas, V. J. Shah, F. Langschied, A. Kalousi, I. Ebersberger, I. Dikic, M. Kaulich

This study uses combinatorial CRISPR screening to identify gene interactions in autophagy, revealing functional buffering and redundant gene circuits.

bioRxiv · Jul 28, 2020Cell Biology

Peptidoglycan editing provides immunity to Acinetobacter baumannii during bacterial warfare

N.-H. Le, K. Peters, A. Espaillat, J. R. Sheldon, J. Gray, G. Di Venanzio, J. Lopez, B. Djahanschiri, E. A. Mueller, S. W. Hennon, P. A. Levin, I. Ebersberger, E. P. Skaar, F. Cava, W. Vollmer, M. F. Feldman

Acinetobacter baumannii incorporates D-Lysine into its peptidoglycan to gain immunity against T6SS attacks from competitors, though this trait is lost in pathogenic strains due to host enzyme activity.

bioRxiv · Apr 23, 2020Microbiology

The evolutionary traceability of proteins

A. Jain, A. von Haeseler, I. Ebersberger

The paper introduces evolutionary traceability to improve the reconstruction of ancient gene sets by distinguishing between true absence and non-detection of orthologs.

bioRxiv · Apr 16, 2018Evolutionary Biology