Author

I. Ganley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. R. Prescott· 2 shared F. Singh· 2 shared A. Ordureau· 1 shared A. Reith· 1 shared E. Barini· 1 shared G. Ball· 1 shared M. Gierlinski· 1 shared M. Muqit· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. R. Prescott

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Global ubiquitylation analysis of mitochondria in primary neurons identifies physiological Parkin targets following activation of PINK1

O. Antico, A. Ordureau, M. Stevens, F. Singh, M. Gierlinski, E. Barini, M. Rickwood, A. R. Prescott, R. Toth, I. Ganley, W. Harper, M. Muqit

The paper identifies 49 PINK1-dependent ubiquitylated proteins in mouse neurons and develops a resource to visualize mitochondrial ubiquitin sites.

bioRxiv · Apr 1, 2021Biochemistry

Pharmacological rescue of impaired mitophagy in Parkinson's disease-related LRRK2 G2019S knock-in mice

F. Singh, A. R. Prescott, G. Ball, A. Reith, I. Ganley

This study shows that the LRRK2 G2019S mutation impairs mitophagy in mice, and that LRRK2 inhibitors can rescue this defect, suggesting a potential therapy for Parkinson's disease.

bioRxiv · Dec 7, 2020Cell Biology