Author

O. Antico

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

M. Muqit· 2 shared V. De Cesare· 2 shared A. Knebel· 1 shared A. Ordureau· 1 shared A. R. Prescott· 1 shared C. Cazzaniga· 1 shared C. Johnson· 1 shared D. Carbajo Lopez· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBiochemistry

M. Muqit

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3 papers

Recent·Most cited

Discovery and characterization of non-canonical E2 conjugating enzymes

S. A. Abdul Rehman, E. Di Nisio, C. Cazzaniga, O. Antico, A. Knebel, C. Johnson, F. Lamoliatte, R. Negri, M. Muqit, V. De Cesare

The paper identifies and characterizes non-canonical E2 conjugating enzymes that ubiquitylate serine and threonine instead of lysine, revealing their target substrate and catalytic mechanism.

bioRxiv · Mar 5, 2023 · PreprintBiochemistry

Global ubiquitylation analysis of mitochondria in primary neurons identifies physiological Parkin targets following activation of PINK1

O. Antico, A. Ordureau, M. Stevens, F. Singh, M. Gierlinski, E. Barini, M. Rickwood, A. R. Prescott, R. Toth, I. Ganley, W. Harper, M. Muqit

The paper identifies 49 PINK1-dependent ubiquitylated proteins in mouse neurons and develops a resource to visualize mitochondrial ubiquitin sites.

bioRxiv · Apr 1, 2021Biochemistry

Deubiquitinating Enzyme Amino Acid Profiling Reveals a Class of Ubiquitin Esterases

S. Virdee, V. De Cesare, D. Carbajo Lopez, P. D. Mabbitt, O. Antico, N. T. Wood

This study profiles DUBs for threonine esterase and lysine isopeptidase activity, revealing that the MJD class specifically exhibits ubiquitin esterase activity.

bioRxiv · May 11, 2020Biochemistry