Author

M. Gierlinski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Assay:imaging· 2 Organism:mouse· 2

Frequent Co-Authors

A. Hartlova· 2 shared J. K. Eykelenboom· 2 shared M. Trost· 2 shared T. U. Tanaka· 2 shared Z. Yue· 2 shared A. Ordureau· 1 shared A. Prescott· 1 shared A. R. Prescott· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

A. Hartlova

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Author profile →

5 papers

Recent·Most cited

Exclusion of condensin I from the nucleus during prophase coordinates mitotic chromosome reorganization to complete sister chromatid resolution

J. K. Eykelenboom, M. Gierlinski, Z. Yue, T. U. Tanaka

This study shows that excluding condensin I from the nucleus during prophase allows condensin II to complete sister chromatid resolution, ensuring correct chromosome segregation.

bioRxiv · Apr 26, 2024Cell Biology

Global ubiquitylation analysis of mitochondria in primary neurons identifies physiological Parkin targets following activation of PINK1

O. Antico, A. Ordureau, M. Stevens, F. Singh, M. Gierlinski, E. Barini, M. Rickwood, A. R. Prescott, R. Toth, I. Ganley, W. Harper, M. Muqit

The paper identifies 49 PINK1-dependent ubiquitylated proteins in mouse neurons and develops a resource to visualize mitochondrial ubiquitin sites.

bioRxiv · Apr 1, 2021Biochemistry

Triggering MSR1 promotes JNK-mediated inflammation in IL-4 activated macrophages

M. Guo, A. Hartlova, M. Gierlinski, A. Prescott, J. Castellvi, J. Hernandez Losa, S. K. Petersen, U. A. Wenzel, B. D. Dill, C. H. Emmerich, S. Ramon y Cajal, D. G. Russell, M. Trost

The paper identifies that MSR1 signaling via K63-polyubiquitylation activates JNK, promoting a pro-inflammatory switch in IL-4 activated macrophages.

bioRxiv · Feb 5, 2019Immunology

Live-cell imaging of marked chromosome regions reveals dynamics of mitotic chromosome resolution and compaction

J. K. Eykelenboom, M. Gierlinski, Z. Yue, N. Hegarat, H. Pollard, T. Fukagawa, H. Hochegger, T. U. Tanaka

The paper uses live-cell imaging to study mitotic chromosome resolution and compaction dynamics, revealing their timing and regulation.

bioRxiv · May 17, 2018Cell Biology

Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib

T. P. Miettinen, J. Peltier, A. Hartlova, M. Gierlinski, V. M. Jansen, M. Trost, M. Bjorklund

This study uses thermal proteome profiling to show palbociclib induces proteasome stabilization and senescence in breast cancer cells via ECM29 loss, with ECM29 mRNA levels linked to relapse-free survival.

bioRxiv · Oct 13, 2017Cancer Biology