Author

I. Garcia-Tunon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. L. Ordonez· 2 shared J. M. Hernandez-Rivas· 2 shared V. Alonso-Perez· 2 shared A. Montano· 1 shared E. Sebastian· 1 shared E. Vuelta· 1 shared F. Sanchez-Guijo· 1 shared J. Hernandez-Sanchez· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

J. L. Ordonez

Mutual co-authors in cluster

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2 papers

Recent·Most cited

CRISPR/Cas9 technology abolishes the BCR/ABL1 oncogene effect in chronic myeloid leukemia and restores normal hematopoiesis

E. Vuelta, J. L. Ordonez, V. Alonso-Perez, L. Mendez, P. Hernandez-Carabias, R. Saldana, J. Sevilla, E. Sebastian, S. Muntion, F. Sanchez-Guijo, J. M. Hernandez-Rivas, I. Garcia-Tunon, M. A. Sanchez-Martin

This study uses CRISPR/Cas9 to target and disrupt the BCR/ABL1 oncogene in CML cells, restoring normal hematopoiesis in mouse models and patient-derived xenografts.

bioRxiv · Aug 5, 2020 · PreprintCancer Biology

ETV6/RUNX1 Fusion Gene Abrogation Decreases The Oncogenic Potencial Of Tumour Cells In A Preclinical Model Of Acute Lymphoblastic Leukaemia.

A. Montano, J. L. Ordonez, V. Alonso-Perez, J. Hernandez-Sanchez, T. Gonzalez, R. Benito, I. Garcia-Tunon, J. M. Hernandez-Rivas

This study abrogates the ETV6/RUNX1 fusion gene in a preclinical model of acute lymphoblastic leukemia, showing reduced oncogenic potential through increased apoptosis and decreased proliferation.

bioRxiv · Oct 18, 2019 · PreprintCancer Biology