Author

G. M. C. Janssen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

P. A. van Veelen· 3 shared A. A. de Waard· 1 shared A. H. de Ru· 1 shared A. Halenius· 1 shared A. Mulder· 1 shared A. Rodriguez Ruiz· 1 shared A. Sapmaz· 1 shared B.-T. Xin· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

P. A. van Veelen

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Author profile →

3 papers

Recent·Most cited

WWP2 osteoarthritis risk allele rs1052429-A confers risk by affecting cartilage matrix deposition via hypoxia associated genes

M. Tuerlings, G. M. C. Janssen, I. Boone, M. van Hoolwerff, A. Rodriguez Ruiz, E. Houtman, E. H. E. D. Suchiman, R. J. P. van der Wal, R. G. H. H. Nelissen, R. Coutinho de Almeida, P. A. van Veelen, Y. F. M. Ramos, I. Meulenbelt

This study investigates how the OA risk allele rs1052429-A affects cartilage matrix deposition through WWP2 upregulation and hypoxia-related genes in a 3D in vitro model.

bioRxiv · Mar 31, 2022 · PreprintCell Biology

PAKC: A novel Panel of HLA class I Antigen presentation machinery Knockout Cells from the same genetic origin

A. A. de Waard, T. Verkerk, M. L. M. Jongsma, K. Hoefakker, S. Sethumadhavan, C. Gerke, S. Bliss, G. M. C. Janssen, A. H. de Ru, F. H. J. Claas, A. Mulder, R. Tampe, P. A. van Veelen, A. Halenius, R. M. Spaapen

The paper generates a panel of APM knockout cell lines to study HLA class I antigen presentation and its role in immune responses.

bioRxiv · Jan 24, 2020Immunology

A Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos

P. P. Geurink, R. Kooij, A. Sapmaz, S. Liu, B.-T. Xin, G. M. C. Janssen, P. A. van Veelen, P. ten Dijke, H. Ovaa

This paper develops a fluorescent small-molecule probe to monitor UCHL1 activity in live cells and zebrafish embryos, showing specificity for UCHL1 over other DUBs.

bioRxiv · Nov 1, 2019Biochemistry